
Hey {{first_name|default:there}}, itβs Vadim π
Congratulations! We made it! π
Six weeks ago, you had a vague sense that you needed "more investors" but no real system for finding them. Today, you've built something most biotech founders never create: a comprehensive, qualified investor pipeline.
Quick recap of what you've assembled & links to the modules:
Week 1: The SIFT System - your methodology for going from scattered to strategic
Week 2: Angels & angel groups - 50+ life science-focused groups with application intel
Week 3: Family offices - 25+ patient capital sources most founders overlook
Week 4: Micro-VCs & emerging managers - 45+ funds writing founder-friendly checks
Week 5: Established VCs - 100+ funds mapped by sector, stage, and recent activity
If you've been following along, you should have 200-400 investor names in your tracker. That's the raw material. This week, we turn it into a weapon.
Today's issue:
The tools that separate hobbyist fundraisers from professionals
How to take your messy list and turn it into a tiered, prioritized, January-ready pipeline
And your bonuses:
The complete "Fundraising System in a Box" - an investor outreach tracker, habit-builder, and mini-CRM
An AI mega-prompt for in-depth investor research to assist you with targeted and informed outreach
So, are you ready? Let's finish what we started :)
FOUNDER STORY
The zombie spreadsheet apocalypse
A few months ago, I was helping a founder prep for his Series A. I was really excited about the companyβs platform technology, which was already showing real traction with early users.
Then I asked to see the investor list.
βGive me a sec,β he said. βItβs in a few different places".β
A few different places turned out to be seven different spreadsheets.
One was a "Top 50 Biotech VCs" list he'd pulled from a LinkedIn post in 2022.
Another was a CSV export from a database trial that expired eighteen months ago.
There was an Excel file labeled "Investors_FINAL_v3_JPM_final" that his former BD lead had started before leaving.
A Google Sheet with 200 names and no context - his intern's summer project from two years back.
And three more fragments: conference badge scans, a purchased list from some "biotech investor database," and random names he'd collected in the Notes app on his phone.
Seven spreadsheets. Maybe 600-700 names total. Zero usable intelligence.
He'd spent two years collecting investors. But he'd never built a system for tracking them. Every few months, he'd start fresh - new spreadsheet, new energy, but the same result.
The old lists would drift into the graveyard, half-finished and abandoned.
Hereβs the thing: As founders, we start with big, audacious goals - and an abundance of energy.
We see the future so clearly. How could it NOT work? And why should this be any different with raising capital?
But, to quote James Clear: "You do not rise to the level of your goals. You fall to the level of your systems."
The founderβs goal was to raise $15M. But his system was a google drive folder full of zombie spreadsheets.
Here's the uncomfortable truth: most founders I work with have some version of this graveyard.
Maybe it's not seven spreadsheets. Maybe it's three. Maybe it's one massive file with 500 rows and no way to tell who's active, who's relevant, or who you've already contacted.
The sourcing work you've done over these six weeks is valuable. But without a system to maintain it, qualify it, and act on it - it'll end up in the graveyard too.
Today, we fix that.
FRAMEWORK
The tools of the fundraising trade
Over the past five weeks, you've learned where to find investors. But sourcing is only half the equation. The other half? Turning names into intelligence.
The challenge is that most founders treat investor research like a Google search. Type in a name, skim the website, maybe check LinkedIn. That's not research, that's trial and error.
Professional fundraisers use systems. They know which investors are actively deploying, which partners to target, what portfolio companies signal about thesis fit, and when a fund is too early or too late in its cycle to lead their round.
This week, I'm giving you that system.
We'll cover the tools landscape (what exists and what it costs), the final SIFT process (turning your 300+ names into a tiered hit list), and the CRM setup that keeps you from starting over every time you raise.
Part 1: The tools landscape
Let's be honest: the paid databases are expensive. Here's what's out there and when each makes sense.
The Enterprise Tier: $5k-$20k/year
PitchBook - Usually the first go-to for VC/PE data. Comprehensive fund profiles, portfolio companies, deal history, partner-level data. Pricing varies by company size and number of seats but typically is in the $8k-20k/year range for a single user. Worth it if you're a serial fundraiser or running BD for multiple companies. For most first-time founders? Overkill.
DealForma - Biotech-specific, great for partnership and M&A deal comps, licensing terms, funding benchmarks. Individual subscriptions start at $18k/year. Excellent for BD and partnership strategy, less essential for pure equity fundraising, especially at pre-seed/seed.
BioCentury / Evaluate - Industry intelligence and analysis. Great for market context and competitive landscape. Enterprise pricing (typically $5k-$10k+). Better suited for later-stage companies or investors.
The verdict: Unless you're raising multiple rounds or advising several companies, these are hard to justify.
The Accessible Tier: $50-$200/month
Crunchbase Pro - $49-99/month or ~$600/year. Best for early-stage investor research. Good filtering, decent VC data, portfolio company tracking. The sweet spot for most biotech founders. You can start here.
Life Science Nation (LSN) - Biotech-focused investor database. Tiered pricing, but more accessible than enterprise tools. Strong for family office and early-stage investor sourcing.
LinkedIn Sales Navigator - $79-99/month. Underrated for investor research. Advanced search, InMail credits, real-time updates. Pairs well with your sourcing work from Weeks 2-5.
The verdict: For most pre-seed to Series A founders, Crunchbase Pro + LinkedIn Sales Navigator covers 80% of what you need.
The Free Tier (what you can do today)
Don't underestimate free resources:
Crunchbase free tier - Limited searches, but enough to verify fund activity
LinkedIn - Partner backgrounds, recent posts, portfolio company announcements
SEC EDGAR - Fund filings, Form D disclosures, actual check sizes
Google Alerts - Track fund announcements, new investments, partner moves
Twitter/X - Many VCs share thesis publicly, announce new funds, engage with founders
AI tools - ChatGPT, Perplexity, Claude for research synthesis (use the mega-prompts I've provided, including the one in todayβs bonus section)
The verdict: You can build a professional-grade pipeline with free tools if you're systematic.
The ROI Framework: When to pay
Ask yourself three questions:
Time vs. money - Can you afford 20 hours of manual research, or is $100/month worth the shortcut?
Frequency - Are you raising once, or will you fundraise again in 18-24 months?
Complexity - Are you targeting a niche (rare disease, specific modality) where filtering saves significant time?
For most first-time founders: Start free. Add Crunchbase Pro when you're actively in fundraising mode. Graduate to enterprise tools only when the math makes sense.
Part 2: The final SIFT - from 300+ names to your target hit list
You've spent five weeks building your investor universe. Now it's time to compress it.
Here's where most founders go wrong: they treat all investors equally. Same outreach, same pitch, same follow-up. That's a recipe for exhausted effort and mediocre results.
The tiering framework
Your final list should have three tiers:
Tier 1: Your "Dream 20" (15-20 investors)
Perfect stage and check size match
Active deployment (invested in last 6-12 months)
Portfolio companies signal thesis fit
Warm intro path exists OR high engagement likelihood
These get your best effort: warm intros, custom outreach, multiple touchpoints
Tier 2: Your "Strong 50" (40-60 investors)
Good fit on fundamentals
Active but slightly less aligned (stage, geography, or thesis)
May require more education or longer timeline
Personalized but templated outreach
Tier 3: Your "Long Shots" (50-100 investors)
Directionally relevant
Unknown deployment status or less clear fit
Worth a swing, but don't over-invest
Efficient, scaled outreach
The qualification scorecard
For each investor in your tracker, score them on five dimensions (1-5 scale):
Stage fit - Do they actually invest at your stage?
Sector fit - Do they have biotech/life science portfolio companies?
Deployment activity - Have they invested in the last 12 months?
Check size match - Does their typical investment match your raise?
Access path - Do you have a warm intro, mutual connection, or clear cold outreach angle?
Scoring:
20-25 points β Tier 1
15-19 points β Tier 2
10-14 points β Tier 3
Below 10 β Remove from active list
Part 3: Your January-ready pipeline
You've sourced. You've qualified. Now you need a system to act.
The simple CRM setup
You don't need Salesforce. You need a single source of truth. Your tracker should include:
Core fields:
Investor name, firm, type (Angel/FO/Micro-VC/VC)
Tier (1/2/3)
Status (Not contacted / Outreach sent / Meeting scheduled / Pass / Follow-up)
Last contact date
Next action + date
Notes (what you learned, what they said)
Intelligence fields:
Recent investments (last 3-6 months)
Fund vintage / deployment status
Decision-maker name + title
Warm intro path (if any)
Thesis alignment notes
The weekly ritual
Starting in January, block 2 hours every Monday:
Review all "Outreach sent" - anyone to follow up?
Move "Meeting scheduled" to prep mode
Queue next batch of Tier 1 outreach
Update notes from any conversations
This rhythm prevents the chaos. No more "wait, did I already email them?" No more lost follow-ups. No more starting from scratch.
The 100-meeting math
Remember: you need 100+ investor meetings to close a round. If 25% of outreach converts to meetings (which is optimistic), you need to contact at least 400 investors.
Your tiered approach means:
Tier 1 (20 investors) β 10-15 meetings (50-75% conversion with warm intros)
Tier 2 (50 investors) β 15-20 meetings (30-40% conversion)
Tier 3 (100 investors) β 10-15 meetings (10-15% conversion)
That's 35-50 meetings from your current list. You'll need to expand and iterate - but now you have a system & a repeatable approach.
YOUR 7-DAY ACTION PLAN
This week is about consolidation and preparation. By next Sunday, you'll have a single, tiered, January-ready investor pipeline.
Days 1-2: Consolidate & clean
Start by mapping the established VC landscape for your specific sector and stage.
Export all investor names from Weeks 2-5 into a single master spreadsheet (use the "System in a Box" template in today's bonus)
Remove duplicates - you'll have overlap between angel groups, family offices, and VC portfolios
Fill in any missing fields: investor type, firm name, sector focus, stage focus
Verify each investor is still active: quick LinkedIn check for recent posts or job changes
Flag any "zombie" entries - investors you added but never researched
Estimated time: 3-4 hours
Days 3-4: Score & qualify
Apply the 5-step scorecard to every investor:
Stage fit (1-5)
Sector fit (1-5)
Deployment activity (1-5)
Check size match (1-5)
Access path (1-5)
Calculate total scores and sort your highest to lowest
Assign tiers based on scores:
20-25 β Tier 1
15-19 β Tier 2
10-14 β Tier 3
Below 10 β Archive (don't delete, just move to a separate tab)
For Tier 1 investors: add notes on why they're a top target and your best path in
Estimated time: 4-5 hours
Days 5-6: Build your hit list
Create your "Dream 20" list - your absolute top-tier targets with warm intro paths
Identify the specific person to contact at each Tier 1 firm (Partner? Principal? Don't guess - research using the Mega Prompt included in the Bonus Resources)
Map warm intro paths: Who do you know who knows them? Check LinkedIn mutual connections, portfolio founder networks, advisor relationships
For investors with no warm path: note their content (podcasts, Twitter, LinkedIn posts) for personalized cold outreach angles (use the Mega Prompt to help with research and customized outreach ideas)
Draft a 1-sentence "why them" for each Tier 1 investor - this becomes your outreach hook
Estimated time: 3-4 hours
Day 7: Set up your system
Finalize your CRM/tracker with all required fields (use the "System in a Box" template)
Set status for all investors to "Not Contacted"
Create a "January Outreach" tab or view with your Tier 1 investors queued first
Block 2 hours on your calendar every Monday in January for pipeline management
Set Google Alerts for your top 10 target firms (fund announcements, new investments, partner news)
Write down your outreach start date - commit to it
Estimated time: 1-2 hours
End of week target:
By Sunday night, you should have:
β A single master tracker with 150-250 qualified investors
β Every investor scored and tiered (Tier 1 / Tier 2 / Tier 3)
β Your "Dream 20" identified with warm intro paths mapped
β A CRM system ready for January outreach
β A calendar reminder to start activating your list
BONUS RESOURCES
BONUS #1: Your fundraising βSystem in a Boxβ
I've built you a complete Google Sheet that consolidates everything from this intensive into a single, ready-to-use toolkit. No more scattered spreadsheets. No more starting from scratch.
What's Inside:
Tab 1: Master Investor Tracker - Your single source of truth for every investor you've sourced.
Tab 2: Qualification Scorecard - The scoring system from today's framework, built into a simple calculator.
Tab 3: Pipeline CRM - A lightweight CRM view filtered to show only investors you're actively working.
Tab 4: Warm Intro Mapper - A dedicated space to map your paths into Tier 1 investors.
Tab 5: Weekly Dashboard - A snapshot view for your Monday pipeline reviews.
Note: the tracker has been pre-populated with values for illustration purposes; please edit as needed.
BONUS #2: The complete investor AI research prompt
One mega-prompt to rule them all. Use this with ChatGPT, Claude, or Perplexity to research any investor on your list. Paste in an investor's name and firm, and get back:
Recent investments (last 12 months)
Fund size and vintage
Thesis and sector focus
Key decision-makers and their backgrounds
Portfolio companies similar to yours
Content they've published (podcasts, posts, articles)
Suggested personalization angles for outreach
THATβS A WRAP!
β¦ and hereβs whatβs next!
Six weeks ago, you started with a vague goal: "find more investors."
Today, you have a system.
You've sourced angels, family offices, micro-VCs, and established funds. You've learned where to find them, how to qualify them, and why fund timing matters more than brand names. You've built a tracker, scored your targets, and tiered your list into Dream 20, Strong 50, and Long Shots.
If youβve done all this work, your fundraising is no longer a vague aspiration. Itβs a pipeline.
But a pipeline without action is just a list.
Which brings us to January.
Coming next week: Activating your investor pipeline
You've built the list. Now it's time to use it - and the timing couldn't be better.
JPM Healthcare Conference kicks off January 13th. For one week, the entire biotech investor ecosystem is concentrated in San Francisco, energized, and actively looking for deals. Even if you're not attending (many founders aren't), this is the highest-signal week of the year to activate your outreach.
Next week, I'll share:
The JPM outreach playbook - how to leverage the conference whether you're there or not
Cold email templates that actually get responses from biotech investors
Warm intro request scripts - exactly what to say when asking for introductions
Timing strategies - when to reach out, when to follow up, and when to wait
The 30-day activation sprint - turning your 200+ names into 20+ meetings
You did the hard work. Now let's make it count.
Before I sign off - a quick note as we close out 2025:
To be honest, building this community started as a thought experiment, and a bit of a βwhat ifβ.
After all, we live in such a noisy world, and I honestly had no idea if anyone would actually want to read about biotech fundraising every Sunday evening :)
But in just 2-3 months, Bio Founder GPS has grown beyond my biggest aspirations. The conversations, the feedback, the potential collaborations that could bear fruit next year - Iβm truly excited, and grateful.
So, if there's one message that I'd like to leave you with as we close out the year, it's this: you are bound for greatness.
Over the past three months, I've been fortunate to speak with many of you who joined this community. And I have to say - there was never a single call that didn't leave me energized. Never a conversation where I thought, "eh, the science is a bit second-rate" or "this company doesn't have real potential."
On the contrary. Every call left me more excited than the last. More convinced that what you're building matters.
So, while I recognize how tough the past few years have been, and how much uncertainty still lingers, I can't help but feel that your success is inevitable.
And if there's a small part I can play in supporting that, well, thereβs not much more that I can ask for :)
Wishing you a restful holiday and a happy New Year.
And if you're attending JPM - let me know! I'll be there and would love to connect in person.
See you next Sunday (and next year)!
To your success,
- Vadim
PS - One quick ask:
Now that we've wrapped the Investor Sourcing Intensive, I'd love your feedback!
Was this series helpful? What worked well, what didn't? Is there anything you'd like me to explore further - corporate VCs, international investors, something else entirely?
A few readers have already reached out asking if I could put all the materials and walkthroughs in one place. Would that be useful to you?
Just hit reply and let me know in a few words. I'd love to support you as we head into the new year!